Plasmodium vivax invasion of human erythrocytes inhibited by antibodies directed against the Duffy binding protein.

Plasmodium vivax invasion of human erythrocytes inhibited by antibodies directed against the Duffy binding protein.

<h4>Background</h4>Plasmodium vivax invasion requires interaction between the human Duffy antigen on the surface of erythrocytes and the P. vivax Duffy binding protein (PvDBP) expressed by the parasite. Given that Duffy-negative individuals are resistant and that Duffy-negative heterozyg...

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Main Authors: Brian T Grimberg, Rachanee Udomsangpetch, Jia Xainli, Amy McHenry, Tasanee Panichakul, Jetsumon Sattabongkot, Liwang Cui, Moses Bockarie, Chetan Chitnis, John Adams, Peter A Zimmerman, Christopher L King
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0040337&type=printable
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https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0040337&type=printable

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