LncRNA PELATON regulates Th2 cell differentiation by miR-10b-5p/GATA3 axis in allergic rhinitis

LncRNA PELATON regulates Th2 cell differentiation by miR-10b-5p/GATA3 axis in allergic rhinitis

Background: Long non-coding RNAs (lncRNAs) have been increasingly recognized as critical regulators in the pathogenesis of immunoinflammatory diseases. Nevertheless, their mechanistic contributions to Th2-driven allergic rhinitis (AR) remain unclear. This study investigated the immunomodulatory func...

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Main Authors: Zhen Liu, MD, Yumei Li, PhD, Xiangkun Zhao, MM, Qi Sun, MD, Yu Zhang, MD, Yaqi Wang, MM, Han Fang, MD, Yujuan Yang, MD, Yakui Mou, MD, Xicheng Song, MD
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:World Allergy Organization Journal
Subjects:
Allergic rhinitis
RNA
Long noncoding
GATA3 transcription factor
MicroRNAs
Th2 cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455125000857
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http://www.sciencedirect.com/science/article/pii/S1939455125000857

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