Suprachoroidal Injection of Topotecan for Retinoblastoma: A Preclinical Study

Purpose: To assess whether levels of topotecan that are expected to be therapeutic against retinoblastoma tumors can be achieved within the retina and choroid by suprachoroidal injection (SCI) and to assess toxicity and safety in vivo. Design: Pharmacokinetics and dose escalation toxicity study. Sub...

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Bibliographic Details
Main Authors: Arun D. Singh, MD, Vishal Raval, MD, Sandeep Kumar, PhD, Anthony Daniels, MD
Format: Article
Language:English
Published: Elsevier 2025-11-01
Series:Ophthalmology Science
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666914525001733
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