Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations

Abstract Biomolecular condensates form via coupled associative and segregative phase transitions of multivalent associative macromolecules. Phase separation coupled to percolation is one example of such transitions. Here, we characterize molecular and mesoscale structural descriptions of condensates...

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Bibliographic Details
Main Authors: Mina Farag, Samuel R. Cohen, Wade M. Borcherds, Anne Bremer, Tanja Mittag, Rohit V. Pappu
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35370-7
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