Guiding the Differentiation Direction of Pancreatic Islet-Derived Stem Cells by Glycated Collagen

The microenvironment is an important factor of stem cells regulating their maintenance, survival, and differentiation. The glycation of proteins with reducing sugars through nonenzymatic reactions induces the collagen cross-linking, which causes tissue stiffening, which is enhanced during aging and...

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Bibliographic Details
Main Authors: Gokhan Duruksu, Aysegul Aciksari
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2018/6143081
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