Numb and NumbL inhibit melanoma tumor growth by influencing the immune microenvironment

Abstract Objective Many investigation have sought to identify therapeutic targets and treatment strategies for skin cutaneous melanoma (SKCM). Numb, an endocytic adaptor protein, is known to act as a tumor suppressor in various human cancers. However, the roles of Numb and its homolog NumbL in immun...

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Bibliographic Details
Main Authors: Siyu Zhang, Lulu Zang, Yingnan Li, Yixin Pang, Yanlong Xin, Yan Zhang, Rufeng Li, Xiaofan Xiong
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Cancer
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Online Access:https://doi.org/10.1186/s12885-024-13191-9
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