Faecalibacterium prausnitzii promotes anti-PD-L1 efficacy in natural killer/T-cell lymphoma by enhancing antitumor immunity

Faecalibacterium prausnitzii promotes anti-PD-L1 efficacy in natural killer/T-cell lymphoma by enhancing antitumor immunity

Abstract Background Natural killer/T-cell lymphoma (NKTCL) is a highly aggressive subtype of lymphoma characterized by a poor prognosis. While immune checkpoint blockade (ICB) therapy has emerged as an effective treatment modality for various cancers, its efficacy among individuals is inconsistent a...

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Bibliographic Details
Main Authors: Zhuangzhuang Shi, Wenxing Jiang, Hongwen Li, Yue Zhang, Weili Xue, Yingjun Wang, Mingzhi Zhang, Zhaoming Li
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medicine
Subjects:
Gut microbiota
Faecalibacterium prausnitzii
Natural killer/T-cell lymphoma
Butyrate
Immunotherapy
Online Access:https://doi.org/10.1186/s12916-025-04230-8
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https://doi.org/10.1186/s12916-025-04230-8

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