Impact of CCL5 gene polymorphisms on coronary artery disease risk and severity in the context of diabetes mellitus

Impact of CCL5 gene polymorphisms on coronary artery disease risk and severity in the context of diabetes mellitus

Abstract Coronary artery disease (CAD) is a major global health burden influenced by genetic and environmental factors. Polymorphisms in the CCL5 gene, which regulates inflammatory responses, have been linked to CAD susceptibility and severity. This study examined the association of -403G/A and In1....

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Main Authors: Hajer Foddha, Ikram Ben Jeddou, Hana Saoud, Saoussen Chouchene, Abdelhak Foddha, Besma Bel Haj Jrad, Hassen Ben Abdennabi, Amel Haj Khelil
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Coronary artery disease
CCL5 gene polymorphisms
Diabetes mellitus
Genetic susceptibility
Gene–environment interactions
Online Access:https://doi.org/10.1038/s41598-025-07785-x
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https://doi.org/10.1038/s41598-025-07785-x

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