Spatiotemporal profiling reveals the impact of caloric restriction in the aging mammalian brain

Summary: Caloric restriction (CR) is a well-studied intervention that extends lifespan and slows cognitive decline across species, yet the specific cell populations and molecular pathways involved remain elusive. In this study, we profiled >500,000 cells from 36 control and CR mouse brains across...

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Bibliographic Details
Main Authors: Zehao Zhang, Alexander Epstein, Chloe Schaefer, Abdulraouf Abdulraouf, Weirong Jiang, Wei Zhou, Junyue Cao
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725009362
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