Mechanism of miR-143 regulating ERK5 signaling pathway-mediated manganese-induced striatal neuronal apoptosis

Mechanism of miR-143 regulating ERK5 signaling pathway-mediated manganese-induced striatal neuronal apoptosis

Overexposure manganese can induce neurotoxicity and apoptosis, in addition, miRNAs are widely involved in the apoptotic process of neurons. Therefore, it is crucial to explore the mechanism of miRNAs in manganese-induced neuronal apoptosis and then to find potential targets. Our present study showed...

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Bibliographic Details
Main Authors: Huan Mao, Yidan Wei, Cheng Liu, Jianmin Yang, Liyu Su, Yuyan Cen, Feng Wang, Deyu Zhu, Yu Deng, Yan Li
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Manganese
miR-143
ERK5 signaling pathway
Striatal
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325006025
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