Accelerated Sarcopenia Phenotype in the DJ-1/<i>Park7</i>-Knockout Zebrafish

Accelerated Sarcopenia Phenotype in the DJ-1/<i>Park7</i>-Knockout Zebrafish

Age-dependent loss of muscle mass and function is associated with oxidative stress. DJ-1/<i>Park7</i> acts as an antioxidant through multiple signalling pathways. DJ-1-knockout zebrafish show a decline in swimming performance and loss of weight gain between 6 and 9 months of age. Here, w...

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Bibliographic Details
Main Authors: Kristine O. Rostad, Tobias Trognitz, Ann Kristin Frøyset, Ersilia Bifulco, Kari E. Fladmark
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Antioxidants
Subjects:
DJ-1
park7
Parkinson’s disease
sarcopenia
skeletal muscle
mitochondria
Online Access:https://www.mdpi.com/2076-3921/13/12/1509
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