Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy

Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy

Abstract The immune evasion is one major challenge for cancer immunotherapy. Despite considerable advancements in immune checkpoint blockade (ICB) therapies for the advanced non‐small cell lung cancer (NSCLC) patients, only a minority of patients receive long‐term survival benefit. Here, this work d...

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Bibliographic Details
Main Authors: Yunfeng Yuan, Qianyu Li, Guoquan Yan, Yifei Qian, Wenyun Guo, Songling Li, Fan Wang, Wanjing Shang, Zijun Zhu, Di Ge, Yanan Wang, Yanfeng Liu
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
immune checkpoint blockade therapy
immune evasion
lysine methyltransferase 5C
non‐small cell lung cancer
STING‐IRF3 signaling
Online Access:https://doi.org/10.1002/advs.202407575
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https://doi.org/10.1002/advs.202407575

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