Evaluating the Effects of Imiquimod on Paths of TLRs and Inflammatory Cytokines Signaling in Infected Macrophages with Leishmania major in Vitro and in Vivo

Background: Leishmania major is an obligate and intracellular pathogen and the macrophages are the cell hosts for L. major. Imiquimod stimulates macrophages to secrete different cytokines via the expression of TLRs. Methods: This study was carried out in the Department of Parasitology, Faculty of M...

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Bibliographic Details
Main Authors: Parisa Ebrahimisadr, Fatemeh Ghaffarifar, Javad Jabari, John Horton, Zohreh Sharifi, Abdolhossein Dalimi, Mohammad Saaid Dayer
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2025-06-01
Series:Iranian Journal of Parasitology
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Online Access:https://ijpa.tums.ac.ir/index.php/ijpa/article/view/4130
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