Effects of a Balanced Translocation between Chromosomes 1 and 11 Disrupting the DISC1 Locus on White Matter Integrity.

Effects of a Balanced Translocation between Chromosomes 1 and 11 Disrupting the DISC1 Locus on White Matter Integrity.

<h4>Objective</h4>Individuals carrying rare, but biologically informative genetic variants provide a unique opportunity to model major mental illness and inform understanding of disease mechanisms. The rarity of such variations means that their study involves small group numbers, however...

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Main Authors: Heather C Whalley, Rali Dimitrova, Emma Sprooten, Maria R Dauvermann, Liana Romaniuk, Barbara Duff, Andrew R Watson, Bill Moorhead, Mark Bastin, Scott I Semple, Stephen Giles, Jeremy Hall, Pippa Thomson, Neil Roberts, Zoe A Hughes, Nick J Brandon, John Dunlop, Brandon Whitcher, Douglas H R Blackwood, Andrew M McIntosh, Stephen M Lawrie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0130900
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https://doi.org/10.1371/journal.pone.0130900

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