Exceptional Antibodies Produced by Successive Immunizations.

Antibodies stand between us and pathogens. Viruses mutate quickly to avoid detection, and antibodies mutate at similar rates to hunt them down. This death spiral is fueled by specialized proteins and error-prone polymerases that change DNA sequences. Here, we explore how B lymphocytes stay in the ra...

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Bibliographic Details
Main Authors: Patricia J Gearhart, Diana P Castiblanco, Lisa M Russell Knode
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.1002321
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