Long-term effect of temporary ART initiated during primary HIV-1 infection on viral persistence

Long-term effect of temporary ART initiated during primary HIV-1 infection on viral persistence

Abstract Initiation of antiretroviral therapy (ART) during primary HIV-1 infection (PHI) has been proposed to limit the formation of HIV-1 reservoirs. However, it remains unknown whether temporary ART initiated during PHI has a long-term effect on viral persistence. Here, we longitudinally quantify...

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Main Authors: Alexander O. Pasternak, Pien M. van Paassen, Yara L. Verschoor, Jelmer Vroom, Karel A. van Dort, Irma Maurer, Marlous L. Grijsen, Ferdinand W. Wit, Godelieve J. de Bree, Neeltje A. Kootstra, Jan M. Prins, Ben Berkhout
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62362-0
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https://doi.org/10.1038/s41467-025-62362-0

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