Clinicopathological Characteristics of HER2-Positive Breast Cancer Patients with BRCA1/2 Pathogenic Variants and Their Response to Neoadjuvant Targeted Therapy

Clinicopathological Characteristics of HER2-Positive Breast Cancer Patients with BRCA1/2 Pathogenic Variants and Their Response to Neoadjuvant Targeted Therapy

ObjectiveTo analyze the proportion and clinicopathological characteristics of HER2-positive breast cancer patients with BRCA1/2 pathogenic variants, and their response to neoadjuvant anti-HER2 targeted therapy. MethodsThe clinicopathological data of 531 breast cancer patients with germline BRCA1/2 p...

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Bibliographic Details
Main Authors: Xingyu LIAO, Huimin LIU, Jie SUN, Li HU, Juan ZHANG, Lu YAO, Ye XU, Yuntao XIE
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2025-06-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
brca1/2 pathogenic variant
her2-positive breast cancer
clinicopathological characteristic
neoadjuvant therapy
Online Access:http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.25.0101
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http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.25.0101

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