Human neutrophil α-defensin HNP1 interacts with bacterial OmpA to promote Acinetobacter baumannii biofilm formation

Abstract Acinetobacter baumannii is the causative agent of a wide range of nosocomial and community-acquired infections that remain extremely difficult to treat due largely to its antibiotic resistance contributed, in part, by biofilm formation. We find that the prototypic human neutrophil α-defensi...

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Bibliographic Details
Main Authors: Chongbing Liao, Qihui Liu, Gan Luo, Yinyue Luo, Dan Yao, Qingxia Wang, Jue Zhang, Yang Wu, Jialin Jin, Dan Xu, Wuyuan Lu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60935-7
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