Therapeutic efficacy of 5-alkylresorcinol on progression of colorectal cancer by activating HCLS1 and suppressing TLR4/MYD88/NF-κB signaling
Abstract Background This study investigates the molecular mechanisms underlying the inhibitory effects of 5-alkylresorcinol (5ARs) on colorectal cancer (CRC) growth. Methods HCT116 cells were treated with 15 μmol/L 5ARs for 24 h, with both control and 5ARs-treated groups undergoing transcriptome seq...
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| Main Authors: | Chun Yang, Jun Yang, Heng Li, Wan Fan, Jian Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
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| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40001-025-02775-1 |
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