Therapeutic efficacy of 5-alkylresorcinol on progression of colorectal cancer by activating HCLS1 and suppressing TLR4/MYD88/NF-κB signaling

Therapeutic efficacy of 5-alkylresorcinol on progression of colorectal cancer by activating HCLS1 and suppressing TLR4/MYD88/NF-κB signaling

Abstract Background This study investigates the molecular mechanisms underlying the inhibitory effects of 5-alkylresorcinol (5ARs) on colorectal cancer (CRC) growth. Methods HCT116 cells were treated with 15 μmol/L 5ARs for 24 h, with both control and 5ARs-treated groups undergoing transcriptome seq...

Full description

Saved in:
Bibliographic Details
Main Authors: Chun Yang, Jun Yang, Heng Li, Wan Fan, Jian Wang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:European Journal of Medical Research
Subjects:
5-alkylresorcinols
Colorectal cancer
HCLS1
TLR4/MYD88/NF-κB signaling pathway
Tumor growth
Targeted therapies
Online Access:https://doi.org/10.1186/s40001-025-02775-1
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s40001-025-02775-1

Similar Items