Capsid protein VP4 of human rhinovirus induces membrane permeability by the formation of a size-selective multimeric pore.

Non-enveloped viruses must deliver their viral genome across a cell membrane without the advantage of membrane fusion. The mechanisms used to achieve this remain poorly understood. Human rhinovirus, a frequent cause of the common cold, is a non-enveloped virus of the picornavirus family, which inclu...

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Bibliographic Details
Main Authors: Anusha Panjwani, Mike Strauss, Sarah Gold, Hannah Wenham, Terry Jackson, James J Chou, David J Rowlands, Nicola J Stonehouse, James M Hogle, Tobias J Tuthill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004294&type=printable
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