Bidirectional modulation of somatostatin-expressing interneurons in the basolateral amygdala reduces neuropathic pain perception in mice

IntroductionNeuropathic pain is characterized by mechanical allodynia and thermal (heat and cold) hypersensitivity, yet the underlying neural mechanisms remain poorly understood.MethodsUsing chemogenetic excitation and inhibition, we examined the role of inhibitory interneurons in the basolateral am...

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Bibliographic Details
Main Authors: Aditya Apte, Julia Fernald, Cody Slater, Marc Sorrentino, Brett Youngerman, Qi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Pain Research
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Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2025.1602036/full
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