The mechanism of enterogenous toxin methylmalonic acid aggravating calcium-phosphorus metabolic disorder in uremic rats by regulating the Wnt/β-catenin pathway

Abstract Background Uremia (UR) is caused by increased UR-related toxins in the bloodstream. We explored the mechanism of enterogenous toxin methylmalonic acid (MMA) in calcium-phosphorus metabolic disorder in UR rats via the Wnt/β-catenin pathway. Methods The UR rat model was established by 5/6 nep...

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Bibliographic Details
Main Authors: Xing Fan, Jing Li, Yan Gao, Lin Li, Haisong Zhang, Zhaoyu Bi
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Medicine
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Online Access:https://doi.org/10.1186/s10020-025-01067-y
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