Development and characterization of long-acting darifenacin intravaginal ring for managing overactive bladder in women: harnessing QbD approach
Abstract Background The oral administration of darifenacin hydrobromide (DBr) is associated with low bioavailability of 15–19% due to poor solubility and extensive first-pass metabolism. Additionally, the conventional oral formulation results in poor patient compliance due to frequent administration...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2025-06-01
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| Series: | Future Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43094-025-00820-8 |
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