Lung surfactant reduces Staphylococcus aureus cytotoxicity and protects host immune cells from membrane damage

ABSTRACT In this study, we identify that lung surfactant significantly reduces the cytotoxicity of Staphylococcus aureus (S. aureus) membrane-damaging toxins. Data demonstrate that natural surfactants from mice and rats and commercially available surfactant, Infasurf, protect human primary cells (ne...

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Bibliographic Details
Main Authors: Maria Predtechenskaya, Corbin J. Arbizzani, Sofia R. Shomento, Timothy R. Borgogna, Jovanka M. Voyich
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:Microbiology Spectrum
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Online Access:https://journals.asm.org/doi/10.1128/spectrum.01386-24
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