Porphyromonas gingivalis induces Zbp1-mediated macrophages PANoptosis in periodonitis pathophysiology

Abstract Periodontitis is an oral immunoinflammatory disease, and macrophages play a crucial role in its pathophysiology. However, macrophage death during antibacterial activities will exacerbate inflammation and tissue damage. Porphyromonas gingivalis is a major constituent of subgingival biofilm p...

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Bibliographic Details
Main Authors: Jin Wu, Zixiang Guo, Long Wang, Yue Shen, Xiang Li, Zhewei Zhang, Xiao Han, Jianlan Zhang, Kunzhan Cai, Chunbo Tang
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01443-y
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