METTL2B m3C RNA transferase: oncogenic role in ovarian cancer progression via regulation of the mTOR/AKT pathway and its link to the tumor immune microenvironment

METTL2B m3C RNA transferase: oncogenic role in ovarian cancer progression via regulation of the mTOR/AKT pathway and its link to the tumor immune microenvironment

Abstract Background Aberrant expression of N3-methylcytidine methyltransferase 2B (METTL2B) has been observed in various human malignancies, including those of the prostate, liver, breasts, and bladder. However, its role in ovarian cancer (OC) remains largely unexplored. This research preliminarily...

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Bibliographic Details
Main Authors: Yizi Meng, Yimei Meng, Hui Zheng, Jinru Huo, Peiling Li, Yanhong Shan, Jin He
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Cancer
Subjects:
Ovarian cancer
N3-methylcytidine
METTL2B
Immune infiltration
Online Access:https://doi.org/10.1186/s12885-024-13225-2
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https://doi.org/10.1186/s12885-024-13225-2

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