YTHDC2 manipulates anti-tumoral macrophage polarization and predicts favorable outcomes in triple negative breast cancer

Abstract Triple-negative breast cancer (TNBC) possesses high malignant and metastatic rates among all subtypes. Chemotherapy is a standard of care for TNBC but only a small moiety of patients achieved complete relief (CR) after chemotherapy. The recent concept of tumor ecosystem has provided new ins...

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Bibliographic Details
Main Authors: Hao Jin, Dongbo Zhang, Yufan Ma, Lanlan Meng, Songyin Huang, Hongjun Su, Jiannan Xu, Yandan Yao
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00880-2
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