LC-MS-MS Measurements of Urinary Creatinine and the Application of Creatinine Normalization Technique on Cotinine in Smokers’ 24 Hour Urine

A simple and sensitive high performance liquid chromatography-tandem mass spectrometry (HPLC-ESI-MS-MS) method was developed and validated for the quantification of creatinine in human urine. The analysis was carried out on an Agilent Zorbax Eclipse XDB-C18 column (2.1×150 mm, 3.5 μm). The mobile ph...

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Bibliographic Details
Main Authors: Hongwei Hou, Wei Xiong, Xiaotao Zhang, Dongkui Song, Gangling Tang, Qingyuan Hu
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2012/245415
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