Astrocyte-derived extracellular vesicular NFIA mediates obesity-associated cognitive impairment

Astrocyte-derived extracellular vesicular NFIA mediates obesity-associated cognitive impairment

Abstract Background The escalating global prevalence of cognitive decline associated with obesity represents a significant public health challenge. Emerging evidence implicates astrocyte-derived extracellular vesicles (ADEVs) as key mediators in the pathogenesis of neurodegenerative disease, positio...

Full description

Saved in:
Bibliographic Details
Main Authors: Lining Wu, Liyun Deng, Xiaolin Xu, Haiqing Chang, Changliang Liu, Jiahui Wu, Changteng Zhang, Ruiqun Wang, Rui Gao, Hai Chen, Shixin Ye-Lehmann, Zhi Zhang, Tao Zhu, Chan Chen
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Neuroinflammation
Subjects:
Obesity
Cognitive impairment
Extracellular vesicles
Astrocytes
NFIA
Synaptic injury
Online Access:https://doi.org/10.1186/s12974-025-03473-9
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12974-025-03473-9

Similar Items