Ursodeoxycholic Acid Influences the Expression of p27kip1 but Not FoxO1 in Patients with Non-Cirrhotic Primary Biliary Cirrhosis

Background. Enhanced expression of cell cycle inhibitor p27kip1 suppresses cell proliferation. Ursodeoxycholic acid (UDCA) delays progression of primary biliary cirrhosis (PBC) but its effect on p27kip1 expression is uncertain. Aims. To analyze the expression of p27kip1 and its transcription modulat...

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Bibliographic Details
Main Authors: Malgorzata Milkiewicz, Justyna Kopycińska, Agnieszka Kempińska-Podhorodecka, Tara Haas, Dimitrios P. Bogdanos, Elwyn Elias, Piotr Milkiewicz
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2014/921285
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