The translational inhibitor 4EBP/Thor is required for Drosophila adaptation to hypoxia
Abstract Adaptation to hypoxia requires the activation of concerted cellular mechanisms mainly dependent on the transcription factor HIF/Sima. 4E-BP/Thor is a CAP-dependent translation inhibitor involved in several cellular and developmental processes, which has been previously shown to be required...
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| Main Authors: | Eleonora Sorianello, Maximiliano J. Katz, Julieta M. Acevedo, Mariana Melani, Joel I. Perez-Perri, Pablo Wappner |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-94457-5 |
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