Formulation and In Vitro Evaluation of Matrix Tablets Containing Ketoprofen–Beta Cyclodextrin Complex for Enhanced Rheumatoid Arthritis Therapy: Experimental and Computational Insights

Formulation and In Vitro Evaluation of Matrix Tablets Containing Ketoprofen–Beta Cyclodextrin Complex for Enhanced Rheumatoid Arthritis Therapy: Experimental and Computational Insights

<b>Background:</b> Rheumatoid arthritis is a chronic autoimmune disease that leads to severe disability and requires improved therapeutic strategies to optimize anti-inflammatory treatment. This study aimed to address this challenge by developing and characterizing an extended-release po...

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Main Authors: Monica Stamate Cretan, Lacramioara Ochiuz, Vlad Ghizdovat, Monica Molcalut, Maricel Agop, Carmen Anatolia Gafițanu, Alexandra Barsan (Bujor), Mousa Sha’at, Ciprian Stamate
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceutics
Subjects:
compressed tablets
ketoprofen
beta cyclodextrin
drug complexes
mathematical models
dissolution test
Online Access:https://www.mdpi.com/1999-4923/17/4/474
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