The Ongoing Challenge of Hematopoietic Stem Cell-Based Gene Therapy for β-Thalassemia

β-thalassemia is characterized by reduced or absence of β-globin production, resulting in anemia. Current therapies include blood transfusion combined with iron chelation. BM transplantation, although curative, is restricted by the matched donor limitation. Gene therapy, on the other hand, is promis...

Full description

Saved in:
Bibliographic Details
Main Authors: Ekati Drakopoulou, Eleni Papanikolaou, Nicholas P. Anagnou
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.4061/2011/987980
Tags: Add Tag
No Tags, Be the first to tag this record!