MAFF mitigates oxidative stress and pyroptosis in cardiopulmonary bypass-induced myocardium injury

MAFF mitigates oxidative stress and pyroptosis in cardiopulmonary bypass-induced myocardium injury

BackgroundCardiopulmonary bypass (CPB) remains an indispensable technique for open-heart surgery; however, it induces systemic inflammation and oxidative stress, leading to myocardial cell damage and compromised prognosis. Optimizing myocardial protection during CPB remains a critical objective. Thi...

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Bibliographic Details
Main Authors: Lei Yuan, Duo Wang, Yale Su, Long Yuan, Mixia Li, Dongdong Zheng, Cuilin Zhu, Hulin Piao, Yong Wang, Zhicheng Zhu, Dan Li, Tiance Wang, Kexiang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Physiology
Subjects:
cardiopulmonary bypass
myocardial injury
bioinformatics
MAFF
reactive oxygen species
pyroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1516167/full
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https://www.frontiersin.org/articles/10.3389/fphys.2025.1516167/full

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