Comparative analysis of CDR3 length-dependent patterns in VHHs

IntroductionVHHs, or nanobodies, are distinguished by their compact size, high stability, and unique ability to selectively target specific epitopes. The CDR3 region in VHHs, which plays a crucial role in antigen binding, exhibits significant diversity and varies among species.MethodThis study syste...

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Bibliographic Details
Main Authors: Lu Zhang, Tianyu Yang, Yao Zhang, Jiahui Yan, Jiaguo Li, Wenfeng Xu, Weimin Zhu, Xinhao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1647230/full
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