Investigating the active components and mechanistic effects of Forsythia suspensa Leaf against RSV via the PI3K/Akt-NLRP3 pathway

Investigating the active components and mechanistic effects of Forsythia suspensa Leaf against RSV via the PI3K/Akt-NLRP3 pathway

Background: Pulmonary infections resulting from respiratory syncytial virus (RSV) continue to pose a significant threat to the well-being of infants and the elderly, but there is no safe, effective and specific treatment except symptomatic treatment. Forsythia Suspensa Leaf (FSL) is cold in nature a...

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Bibliographic Details
Main Authors: Xiaoxue Wang, Weilian Ren, Ping Wang, Li Dong, Haitao Du, Na Li, Guixia Liu, Ru Zhang, Lin Wang, Tiefeng Sun
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
Subjects:
Respiratory syncytial virus
BALB/C mice
Forsythia suspensa Leaf
Phillyrin
Active ingredient
Rosmarinic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024143162
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