Alveolar epithelial type 2 cell specific loss of IGFBP2 activates inflammation in COVID-19

Alveolar epithelial type 2 cell specific loss of IGFBP2 activates inflammation in COVID-19

Abstract The coronavirus disease 2019 (COVID-19) global pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, our understanding of SARS-CoV-2-induced inflammation in alveolar epithelial cells remains very limited. The contributions of intracellular insulin-like...

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Main Authors: Valentina Pujadas, Chiahsuan Chin, Narendra V. Sankpal, James Buhrmaster, Ashwini Arjuna, Rajat Walia, Michael A. Smith, Oliver Eickelberg, Ross M. Bremner, Thalachallour Mohanakumar, Angara Sureshbabu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Respiratory Research
Online Access:https://doi.org/10.1186/s12931-025-03187-9
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https://doi.org/10.1186/s12931-025-03187-9

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