Serum heat inactivation diminishes ApoE-mediated uptake of D-Lin-MC3-DMA lipid nanoparticles

Serum heat inactivation diminishes ApoE-mediated uptake of D-Lin-MC3-DMA lipid nanoparticles

Nanoparticles play a crucial role in drug delivery research. The protein corona that develops on the surface of nanoparticles after administration has garnered substantial attention due to the significant effects it has on their performance. Lipid nanoparticles (LNPs) depend on protein corona format...

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Bibliographic Details
Main Authors: Demian van Straten, Luuk van de Schepop, Rowan Frunt, Pieter Vader, Raymond M. Schiffelers
Format: Article
Language:English
Published: Beilstein-Institut 2025-05-01
Series:Beilstein Journal of Nanotechnology
Subjects:
apolipoprotein e
fetal calf serum
heat inactivation
lipid nanoparticle
protein corona
Online Access:https://doi.org/10.3762/bjnano.16.57
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https://doi.org/10.3762/bjnano.16.57

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