Dual-functional probiotic hydrogel with puerarin integration for microbiota-neuroimmune regulation in antibiotic-free periodontitis therapy

Periodontitis is an inflammatory disease caused by the imbalance of the periodontal microbial ecosystem. Traditional treatment methods not only kill pathogenic bacteria but also inhibit the growth of beneficial bacteria, thereby disrupting the balance of the oral microbial ecosystem. In this study,...

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Main Authors: Yi Wang, Yansheng Qu, Xiangmei Liu, Jin Huang, Congyang Mao, Chaofeng Wang, Shengli Zhu, Yufeng Zheng, Zhaoyang Li, Zhenduo Cui, Hui Jiang, Yang Lv, Jie Shen, Shuilin Wu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-11-01
Series:Bioactive Materials
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Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2500297X
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