Matrix metalloproteinase-driven epithelial-mesenchymal transition: implications in health and disease
Abstract Epithelial–mesenchymal transition (EMT) is a process in which epithelial cells, defined by apical–basal polarity and tight intercellular junctions, acquire migratory and invasive properties characteristic of mesenchymal cells. Under normal conditions, EMT directs essential morphogenetic eve...
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| Main Authors: | Ghazaleh Khalili-Tanha, Evette S. Radisky, Derek C. Radisky, Alireza Shoari |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-04-01
|
| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-025-06447-w |
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