Matrix metalloproteinase-driven epithelial-mesenchymal transition: implications in health and disease

Abstract Epithelial–mesenchymal transition (EMT) is a process in which epithelial cells, defined by apical–basal polarity and tight intercellular junctions, acquire migratory and invasive properties characteristic of mesenchymal cells. Under normal conditions, EMT directs essential morphogenetic eve...

Full description

Saved in:
Bibliographic Details
Main Authors: Ghazaleh Khalili-Tanha, Evette S. Radisky, Derek C. Radisky, Alireza Shoari
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06447-w
Tags: Add Tag
No Tags, Be the first to tag this record!