BaCoN (Balanced Correlation Network) improves prediction of gene buffering

Abstract Buffering between genes, where one gene can compensate for the loss of another gene, is fundamental for robust cellular functions. While experimentally testing all possible gene pairs is infeasible, gene buffering can be predicted genome-wide under the assumption that a gene’s buffering cap...

Full description

Saved in:
Bibliographic Details
Main Authors: Thomas Rohde, Talip Yasir Demirtas, Sebastian Süsser, Angela Helen Shaw, Manuel Kaulich, Maximilian Billmann
Format: Article
Language:English
Published: Springer Nature 2025-04-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/s44320-025-00103-7
Tags: Add Tag
No Tags, Be the first to tag this record!