Cyclization Modes in Anilides of <i>N</i>-Protected 3-Oxo-4-phenylaminobutyric Acid Under Knorr Conditions

Anilides of 3-oxo-4-phenylaminobutyric acid with Troc or COOEt protection at the phenylamino group undergo competing cyclization processes in neat polyphosphoric acid at 80 °C. Depending on the protecting group and the duration of the process, three main products in different ratios are formed. Alon...

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Bibliographic Details
Main Authors: Plamen Angelov, Yordanka Mollova-Sapundzhieva
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molbank
Subjects:
Online Access:https://www.mdpi.com/1422-8599/2024/4/M1933
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