Male preference for TERT alterations and HBV integration in young-age HBV-related HCC: implications for sex disparity

Male preference for TERT alterations and HBV integration in young-age HBV-related HCC: implications for sex disparity

Background/Aims Hepatocellular carcinoma (HCC) exhibits significant sex disparities in incidence, yet its molecular mechanisms remain unclear. We explored the role of telomerase reverse transcriptase (TERT) genetic alterations and hepatitis B virus (HBV) integration, both known major contributors to...

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Main Authors: Jin Seoub Kim, Hye Seon Kim, Kwon Yong Tak, Ji Won Han, Heechul Nam, Pil Soo Sung, Sung Won Lee, Jung Hyun Kwon, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Jeong Won Jang
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2025-04-01
Series:Clinical and Molecular Hepatology
Subjects:
hepatocellular carcinoma
telomere
mutation
virus integration
sex
Online Access:http://e-cmh.org/upload/pdf/cmh-2024-0545.pdf
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http://e-cmh.org/upload/pdf/cmh-2024-0545.pdf

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