Chimeric Nanozyme Bacterial Outer Membrane Vesicles Reprograming Tumor Microenvironment for Safe and Efficient Anticancer Therapy

Chimeric Nanozyme Bacterial Outer Membrane Vesicles Reprograming Tumor Microenvironment for Safe and Efficient Anticancer Therapy

Abstract This study presents an innovative approach utilizing a biocompatible shell to shield bacterial outer membrane vesicles (OMVs) and incorporate Fe ions and ultrasmall Au nanoparticles to develop a combined tumor therapeutic strategy. These chimeric nanozyme shells effectively reduce the toxic...

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Bibliographic Details
Main Authors: Fan Zhang, Qianqian Li, Haibing Dai, Weiqun Li, Xiang Chen, Huibin Wu, Shanming Lu, Ran Luo, Feng Li, Guihong Lu, Jianbo Yu, Lin Mei
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
ferroptosis
immunomodulation
nanozyme
outer membrane vesicles
tumor
Online Access:https://doi.org/10.1002/advs.202417712
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https://doi.org/10.1002/advs.202417712

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