The Use of Recombinant Pseudotype Virus-Like Particles Harbouring Inserted Target Antigen to Generate Antibodies against Cellular Marker p16INK4A

Protein engineering provides an opportunity to generate new immunogens with desired features. Previously, we have demonstrated that hamster polyomavirus major capsid protein VP1-derived virus-like particles (VLPs) are highly immunogenic and can be employed for the insertion of foreign epitopes at ce...

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Bibliographic Details
Main Authors: Rita Lasickienė, Alma Gedvilaite, Milda Norkiene, Vaida Simanaviciene, Indre Sezaite, Dovile Dekaminaviciute, Evelina Shikova, Aurelija Zvirbliene
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/263737
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