Evaluation of the effect of metformin as a radiosensitiser in solid tumours: A systematic review

Evaluation of the effect of metformin as a radiosensitiser in solid tumours: A systematic review

Background: Metformin is an antidiabetic drug that has shown its benefit in increasing the effect of radiotherapy in the treatment of solid tumors in preclinical studies. The objective of this systematic review is to study the effect of metformin as a radiosensitizer in studies carried out in clinic...

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Main Authors: Elísabet González del Portillo, Alejandro Olivares-Hernández, Luis Corral Gudino, Laura Corvo Félix, Lorena Bellido Hernández, Luis Posado Domínguez, David León Jiménez, Rogelio González Sarmiento, Edel del Barco Morillo, Emilio Fonseca Sánchez, José Pablo Miramontes-Gonzáleze
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Metformin
Radiosensitiser
Solid tumours
Systematic review
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630825000205
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