Refuse in order to resist: metabolic bottlenecks reduce antibiotic susceptibility

The growth of pathogenic bacteria in the host is a prerequisite for infectious diseases. Antibiotic drugs are used to impair bacterial growth and thereby treat infections. In turn, growth of bacteria is underpinned by their primary metabolism. Thus, it has long been recognized that the activity of a...

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Bibliographic Details
Main Authors: Orestis Kanaris, Frank Schreiber
Format: Article
Language:English
Published: Springer Nature 2025-02-01
Series:Molecular Systems Biology
Online Access:https://doi.org/10.1038/s44320-025-00089-2
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