Heterologous expression of the M. abscessus CBASS system confers phage TM4 resistance in M. smegmatis
Abstract Phage therapy for multidrug-resistant Mycobacterium abscessus is constrained by the narrow lytic spectrum of phages due to unknown antiphage mechanisms. Bacteria deploy various defense strategies to prevent phage infection, but few have been comprehensively characterized in mycobacteria. My...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | BMC Microbiology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12866-025-04214-x |
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